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Senior scientist (chemistry), chemical development

Dublin
Astrazeneca
Scientist
Posted: 30 January
Offer description

Location
Dublin
Responsibilities
As a Senior Scientist you will support the technical contribution to transfer, maintain and optimise supply for one or more AstraZeneca commercial products.
You will identify, develop and implement process improvements for both launch and commercial products through the use of existing and cutting-edge technologies.
You will also provide expert technical input through laboratory experimentation, in-silico modelling and direct manufacturing support at our internal AZ API manufacturing site in Dublin.
Your role will also involve contribution to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product.
Qualifications
BSc/PhD level education in a relevant discipline and experience working within a Research & Development or Manufacturing environment in the pharmaceutical industry.
Technical expertise and understanding of practical synthetic organic chemistry spanning both lab and manufacture.
Experience in the Tech Transfer of pharmaceutical small molecule Drug Substance processes.
Background in dealing with the challenges of both the scale up and scale down of processes.
A good understanding of the overall drug development process from discovery through to launch.
A thorough understanding of the principles and management of SHE and cGMP.
Excellent communication and strategic influencing skills across interfaces of discipline, culture, and expertise both internally and externally.
Proven problem solver with in depth technical skills.
Proficiency in the use of statistics to understand data.
Ability to think and operate across functional boundaries, challenge the status quo and seek opportunities for business improvement.
Desirable Skills
Experience of delivering CMC content or contributions to regulatory filings throughout the life cycle of process development in the pharmaceutical industry.
Experience working within a Research & Development and Manufacturing environment in the pharmaceutical industry.
Experience of technical supervision and leading small teams of people or scientific projects.
Experience of late stage development or commercial supply with a background in a process chemistry skill group.
Experience of working across skillsets (e.g. with chemists, analysts and physical properties experts).
EEO and Accommodation
We welcome applicants from all qualified candidates, regardless of characteristics, and comply with equal employment opportunity laws.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
Please contact us to request accommodation.
Date Posted / Closing Date
Posted 14-Jan-**** | Closing 27-Jan-****
#J-*****-Ljbffr

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