Product Lifecycle Management (PLM) Specialist
This position is responsible for managing our Product Lifecycle Management (PLM) system, the process of managing the entire life span of a product from idea generation, through design and development, to production, to service in the field, and ultimately disposal – it integrates people, processes, and technologies across the enterprise.
This position supports all PLM users within the Applied business unit, conducts ongoing training, and helps facilitate PLM tasks across functional departments. In addition to the responsibilities as the PLM power user, this person will be part of a global team to align multiple sites within Applied business and other business units around processes within the PLM system.
Act as change agent for the Applied business unit.
Assist global teams with the preparation of data prior to migration to Windchill PLM, by assessing the current landscape of our current PDM system and develop migration strategy.
Technical lead within Applied org. for all PLM related activities.
Represent the Applied org. in enterprise-wide best business practices.
Develop training plan for initial launch of PLM for all users within JCI Applied business unit and provide continuous training for new functionalities.
Work with each of the Integrated Product Teams (IPTs) to determine the current and future PLM requirements.
Monitor development within the industry and propose future changes to the PLM platform based on developments within the software or updates in industry practices.
What we look for
5-10 years’ experience and strong familiarity with Windchill PLM.
Experienced in leading deployment of PLM in a large multi-national org.
Experience with engineering change management.
Bachelor’s degree or equivalent experience required.
Experience with 3D Modeling software (Creo, Solidworks, Inventor) is required. Creo is preferred.
Proficiency with ERP systems (SAP) is strongly preferred.
Excellent communication skills – verbal, written, ability to present. English language is a must.
Extraordinary organizational skills with the ability to prioritize and follow through on all work.
Ability to work with all levels of the organization.
Microsoft Office applications is preferred.
Travel up to 10% of the time.
Product Lifecycle Mechanical Engineer, Data Center Mechanical Solutions
AWS Infrastructure Services owns the design, planning, delivery, and operation of all AWS global infrastructure. In other words, we're the people who keep the cloud running. We support all AWS data centers and all of the servers, storage, networking, power, and cooling equipment that ensure our customers have continual access to the innovation they rely on. We work on the most challenging problems, with thousands of variables impacting the supply chain – and we're looking for talented people who want to help.
You'll join a diverse team of software, hardware, and network engineers, supply chain specialists, security experts, operations managers, and other vital roles. You'll collaborate with people across AWS to help us deliver the highest standards for safety and security while providing seemingly infinite capacity at the lowest possible cost for our customers. And you'll experience an inclusive culture that welcomes bold ideas and empowers you to own them to completion.
Amazon Web Services is seeking a mechanical engineer to be part of a global engineering team responsible for ownership and continuous improvement related to data center liquid cooling infrastructure products within our rapidly expanding data center footprint. We seek engineers with hands‑on mechanical and manufacturing experience in liquid cooling products. Experience leading cooling product design, understanding cooling principles, and knowledge of quality manufacturing practices is essential. You should comprehend detailed equipment specifications, piping systems, pumping systems, air handler systems, and evaluate design change implications.
As a Global Amazon Product Lifecycle Engineer, you'll support AWS data centers' liquid cooling infrastructure. You'll work with product development teams to understand products during development and testing, maintaining engineering ownership throughout operational life. You'll serve as the global engineering resource for liquid cooling AWS infrastructure in data centers.
Amazon has a global presence. Intermittent travel will be necessary and should be expected to be around 30%. Some travel will be domestic, but international travel will be necessary. This position can be based out of Dublin, IRL.
Key job responsibilities
Possess strong engineering judgement and are able to provide recommendations despite uncertainty.
Are detail and data oriented.
Have experience engineering air handling, piping and/or pumping products.
Review, update, and approve equipment submittals.
Work with global liquid cooling equipment suppliers and manufacturers.
Build trust and relationships with different stakeholders (e.g. reliability, operations, design, compliance).
Work on concurrent projects, in multiple geographic zones.
Understand and explain complex systems in clear and concise language.
Support Operations including failure mode and root cause analysis, maintenance and troubleshooting support, and operating procedure review for both mechanical and electrical issues.
Listen to the voice of the customer to understand if there are improvements that can be made to increase product reliability or availability.
Work with global supplier and manufacturers to design product improvements, and to oversee root cause analysis.
Contribute to our global body of knowledge and drive a cycle of continuous improvement at a global scale.
Amazon is an equal opportunities employer. We believe passionately that employing a diverse workforce is central to our success. We make recruiting decisions based on your experience and skills. We value your passion to discover, invent, simplify and build. Protecting your privacy and the security of your data is a longstanding top priority. Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability status, or other legally protected status.
Senior QA Specialist, Biologics Drug Substance (Remote / Home Based)
The Biologics Drug Substance Senior Quality Assurance Specialist is responsible for performing key quality tasks in respect of Company Biologics products. Work in the External Manufacturing Quality Group within the Technical Operations department, which oversees contract manufacturing operations, as well as Internal Quality Systems. Reporting directly to the Drug Substance Lead, External Manufacturing QA.
Essential Functions/Responsibilities
Monitoring the daily operations at the Contract Manufacturer, performing batch review and disposition, reviewing and approving product complaints, deviations, Validation protocols, change controls and leading product related investigations.
CMO Batch file and product testing record review and approval. Associated lot Disposition activity.
Ensuring compliance of all respective contract manufacturers to both internal Jazz requirements and country specific regulations.
Collaboration with all contract manufacturers, packagers and testing laboratories to resolve any quality issues.
Contributing to the successful outcome of all regulatory inspections associated with company business, both internally and at contract manufacturers, as required.
Highlighting any risks associated with maintaining supply of commercial drug products to all markets.
Conducting vendor audits and vendor site visits as required.
Assisting in internal audits and regulatory agency inspections.
Summarizing CMO Annual Product Quality Reviews and supporting regulatory submissions.
Assist with the generation of Jazz APQR (Annual Product Quality Review).
Maintaining product related Quality Technical Agreements (QTAs).
Understanding new regulations and guidelines, as they apply to the company business and implement systems and procedures to incorporate these new regulations as appropriate.
Review and approve moderate complexity deviations and associated corrective actions.
Support the generation of new, as well as improvement of, existing department SOPs.
Support delivery of projects.
Work with management to resolve project issues and resource constraints within the team.
Liaise with the internal and external stakeholders to resolve and clarify any point of issue.
Review and approve less complex validation documents.
Partner with other departments/groups to problem‑solve and address moderately complex issues.
Collaborate in the continuous improvement of the QA processes, identifying opportunities and leading them up to the implementation.
Represent QA in cross‑functional project teams for moderately difficult projects.
Participate in and facilitate regulatory inspection readiness.
Coordinates and collaborates with other teams to meet organizational goals and work requirements.
Receives assignments in the form of objectives and determines how to use resources to meet schedules and goals.
Follows processes and operational policies in selecting methods and techniques for obtaining solutions; solves moderately complex problems and can identify viable and often innovative options.
Uses analytical skills and judgment to recommend the "best" solution.
Demonstrates success using compliance knowledge, creativity, and regulatory perspectives to solve problems, especially those associated with major and critical deviations.
Maintain quality from cell banking through to production and post‑release events (e.g., stability, product complaints).
Required Knowledge, Skills, and Abilities
Strong knowledge of GMP and Regulatory Compliance as applicable to the Pharmaceutical/ Biotechnology Industry.
Ability to understand and apply GMP regulations as they relate to manufacturing, QC analytical testing, and facility operations, deep knowledge of Biologics manufacturing.
Substantial experience working in or directly supporting manufacturing within a biologics drug substance manufacturing site.
Experience with contract manufacturing is desirable.
Significant experience (>5 years) of commercial and/or late stage clinical phase GMP manufacturing of biologics.
Highly organized, with exceptional time management and prioritization.
Excellent verbal and written communication skills.
Experience in Drug Product Manufacture in addition to Drug Substance an advantage.
QP eligibility or progress toward QP certification is highly desirable.
Required/Preferred Education and Licenses
Bachelor’s degree in pharmacy, chemistry, biotechnology, biochemistry, microbiology or a related discipline.
Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.
Project Analyst
The Project Analyst is responsible for managing the financial performance of assigned projects by ensuring accurate cost tracking, timely reporting, and effective financial controls. This role works closely with project managers, operations teams, Plant Controller and senior leadership to support budgeting, forecasting, billing, and compliance activities.
How you will do it
Monitor, track, and analyze project costs, budgets, and financial performance.
Prepare Bi-Weekly project cost reports, variance analyses, and financial summaries.
Maintain accurate job costing, including labor, materials, equipment, and subcontractor expenses.
Support project managers in understanding financial results and cost drivers.
Prepare and process progress billings, milestone invoices, and time‑and‑materials billing.
Review contracts to ensure billing aligns with terms, rates, and deliverables.
Track accounts receivable and unbilled accounts.
Ensure revenue recognition complies with company policies and accounting standards.
Ensure jobs are reconciled and closed in a timely manner.
Budgeting & Forecasting
Assist in developing project budgets and financial forecasts.
Update forecasts based on actual performance and projected costs.
Identify cost overruns, risks, and opportunities for savings.
Assist in the backlog reporting by region.
Assist in secured weekly reporting by region.
Work with Sales team to ensure sales force is updated correctly.
Assist in the backlog flow for accurate reporting.
Compliance & Documentation
Maintain accurate project financial records and documentation.
Ensure compliance with internal controls, audit requirements, and client reporting standards.
Support internal and external audits related to project financials.
Work closely with project managers, procurement, and operations teams.
Provide financial insights to support decision‑making.
Communicate project financial results clearly and professionally to stakeholders.
Work closely with the Plant Controller to ensure alignment.
What we look for
Diploma or degree in Accounting, Finance, or Business Administration.
2–5+ years of experience in project accounting or cost control.
Strong understanding of project accounting principles and job‑costing methods.
Proficiency with accounting software (Sage300, SAP, or similar).
Excellent attention to detail and organizational skills.
Ability to manage multiple projects and deadlines.
Strong communication and problem‑solving abilities.
Experience in the Manufacturing or Construction industry preferred.
Senior Mechanical Design Engineer - Offsite Manufacturing
The Senior Mechanical Design Engineer will play a key technical role within the Modular Design Engineering Team, responsible for the end‑to‑end mechanical design of offsite‑manufactured, factory‑built modular systems. These include modular data centres, packaged MEP plantrooms, and skid‑mounted mechanical assemblies.
The role requires proven experience in offsite manufacturing and modular construction, with designs developed specifically for Design for Manufacture and Assembly (DfMA), factory assembly, testing, certification, transportation, and repeatable deployment across global regions.
What we look for
Degree in Mechanical Engineering or equivalent.
8+ years experience in mechanical building services or industrial MEP design.
Demonstrable experience in offsite manufacturing and modular construction (core requirement).
Experience delivering modular or packaged mechanical systems for data centres or other mission‑critical facilities.
Strong expertise in chilled water systems, pumping, and thermal management.
Experience producing factory‑ready design documentation suitable for fabrication and testing.
Experience with liquid‑cooled data centre systems.
Familiarity with UL / cURus, CE, PED, ASHRAE, EN, and ISO standards.
Chartered Engineer or working toward chartership.
Experience working across multiple regions (EU, US, Middle East).
Occasional travel to manufacturing facilities or project sites may be required.
Senior Product Engineering Manager - HVAC (EU market)
The Senior Product Engineering Manager – HVAC leads the engineering development and full product lifecycle of data‑centre chillers and commercial heat‑pump systems for the European market.
What you will do
Lead the engineering development and full product lifecycle of data‑centre chillers and commercial heat‑pump systems for the European market.
Own the technical delivery of HVAC products, ensuring they meet EU performance, safety, environmental, and regulatory requirements.
Translate customer needs, regulatory obligations, and market insights into clear, robust engineering solutions.
Drive cost, quality, reliability, and efficiency improvements across existing and new products.
Support prototype builds, laboratory and field testing, certification, and customer validation activities across Europe.
Mentor and develop engineering team members, fostering a culture of technical excellence and continuous improvement.
Act as a key technical partner to Product Management, Operations, Quality, Supply Chain, Service teams, and global engineering centres.
How you will do it
Deliver end-to-end engineering ownership, from concept through design, validation, industrialisation, and lifecycle management.
Develop and review engineering specifications, CAD designs, calculations, test plans, P&IDs, and RFQs.
Coordinate multidisciplinary engineering inputs across mechanical, electrical, controls, and compliance domains.
Apply LEAN engineering methodologies (A3, 8D, value-stream mapping, standard work) to improve speed, quality, and predictability.
Ensure compliance with relevant EU regulations and standards, including Ecodesign/ErP, low‑GWP refrigerant requirements, and CE conformity.
Partner with manufacturing and supply chain teams to enable design-for-manufacture and design-for-service.
Collaborate closely with global design hubs in York (US) and Wuxi (China) to align platforms and best practices.
What we look for
Degree (Bachelor’s or Master’s) in Mechanical, Thermal, or Energy Engineering.
7–12 years’ experience in HVAC product engineering, ideally within chillers and/or heat‑pump technologies.
Strong technical knowledge of thermodynamics, HVAC/R system design, and low‑GWP refrigerants.
Proven experience working with EU regulations and standards, including:
EN 378
EU F‑Gas Regulation
Pressure Equipment Directive
Machinery Directive
ATEX Directive
Electrical safety of machinery
ISO/EN and national building & ventilation standards
Demonstrated success applying LEAN engineering practices in a product development environment.
Strong problem‑solving, collaboration, and documentation skills.
Fluency in English; additional European languages are an advantage.
All candidates are considered for equal employment opportunities.
All postings comply with likewise equality and non-discrimination policies.
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