Job Title: Postdoctoral Researcher Department: School of Pharmacy and Biomolecular Sciences Reporting to: Dr Roger Preston Location: St Stephen's Green, Dublin Contract/Duration: Specified purpose contract, up to 12 months (with possibility of extension) Remuneration: Dependent upon candidate experience Closing Date: 26th of November 2025 at 5pm RCSI is a community of academic, research, clinical and professional staff working collaboratively to lead the world to better health. Here, you will thrive in an innovative and inclusive atmosphere and your personal development and wellbeing will be supported. We invite you to join us to help deliver on our exciting mission "To educate, nurture and discover for the benefit of human health". We seek candidates whose experience to date has prepared them to contribute to our commitment to the "Race Equality Action Plan 2025-2029" at RCSI. Our students come from all walks of life and so do we. We hire great people from a wide variety of backgrounds. This makes our university stronger and ensures we hire the best talent. Innovating for a Healthier Future 2023-2027 is RCSI's new five-year strategic plan. Through it, RCSI will enhance human health by meeting the health workforce needs of society, creating the insights and inventions that drive health improvements, and working in partnership with patients and the public in support of better health and well-being for all. The strategy unites the RCSI community in supporting the UN Sustainable Development Goals - with a particular focus on Goal 3, which targets good health and well-being. For each of the last six years, RCSI has been positioned in the Top 300 of universities worldwide in the Times Higher World University Rankings. We are proud that RCSI ranks first in the world for "Good Health and Well-being" in the Times Higher Education #SDG #SDG Impact Rankings 2025. This reflects our commitment to supporting people of all ages to live healthy lives and our work to promote the concepts of well-being and positive health. In 2024, RCSI was delighted to be named one of the Sunday Times Best Places to Work in Ireland. At RCSI, our core values of Respect, Collaboration, Scholarship, and Innovation are at the heart of everything we do. We are committed to creating an inclusive and supportive environment where every colleague is valued and empowered to thrive. Our dedication to these values ensures that we foster a culture of mutual respect, open collaboration, continuous learning, and innovative thinking. Join us at RCSI, where your contributions will be recognised, and you will be part of a dynamic team making a real impact on global health. About Our Research RCSI recognises that excellence in research is critical to the quality of its educational activities, its credibility, and, overall, to its mission to enhance human health. RCSI's research strategy aims to build upon its strength in translational biomedical and clinical research to deliver transformational, high impact changes in health care. Targeting both Irish national and EU funding, along with increased collaboration with industry, is a major part of the RCSI research strategy. Forging increased collaboration between RCSI PIs and industry is of critical importance to achieving success in this area. RCSI is also committed to provide its researchers with the supports and developmental opportunities to enable them to continuously grow and support their overall career development. Summary of Post The position will work on a project that aims to investigate the mechanistic role of coagulation factors in regulating inflammation, building on recent discoveries from our group (Leon et al., Nature Communications 2025; Rehill et al., Science Advances 2025). This Research Ireland-funded project will elucidate how components of the coagulation cascade modulate inflammatory cell signalling, with a view to developing novel therapeutic approaches. The successful candidate will work within Dr Roger Preston's laboratory in the School of Pharmacy and Biomolecular Sciences at RCSI, Dublin. Role Overview The successful candidate will use a variety of molecular and cellular techniques to explore crosstalk between the coagulation and inflammation pathways. Experimental methods used in this project will include cell-based coagulation assays, flow cytometry, confocal microscopy, recombinant protein production, cell signalling assays and transcriptomic analysis. The role will elucidate how components of the coagulation cascade modulate inflammatory cell signalling, with a view to developing novel therapeutic approaches. Other objectives and duties of the post are: Work under the direction of the PI to fulfil project goals. Work with and assist junior lab staff members to achieve project objectives. Comply with statutory legislation and department rules and requirements in furtherance of your own and general staff welfare and safety. Undergo programmes of training and development as may be required from time to time. Representing the best interests of the Department/College at all times. Qualifications - (Essential): A PhD in Molecular Biology/Biochemistry/Genetics/Immunology or related biological subject. Knowledge & Experience - (Essential): Relevant experience using molecular and cellular techniques to explore crosstalk between the coagulation and inflammation pathways. Relevant experience with some or all of the experimental methods including - cell-based coagulation assays, flow cytometry, confocal microscopy, recombinant protein production, cell signalling assays and transcriptomic analysis. The ideal candidate would be self-motivated, creative and highly competent, as demonstrated by first-author publications in recognised scientific journals in relevant topics. Experience in haemostasis, vascular biology, or immunology would be advantageous, but not essential. Skills & Competencies: Research Methods: Techniques and experimental methods outlined above Communication Skills: Proven ability to communicate complex ideas. Project Management Skills: Ability to ensure that project plans are communicated and that all timelines are met. Self-starter with the ability to work as part of a team: Ability to operate effectively as part of a team - is supportive, adaptable, and considerate in interactions with others; shares work and information; establishes rapport, can influence and develop effective networks. I.T. skills: Knowledge of MS Office suite. Conscientious: Have a pro-active approach to work, anticipating and resolving problems in advance; have keen attention to detail - from anticipating and addressing issues in advance to understanding requests and delivering quality work with minimal errors. Flexibility: Can operate flexibly within a busy environment; can shift focus when required. Customer Focus: Have strong customer service skills. Be able to communicate with a high level of initiative, tact, diplomacy and confidentiality. Motivated: Display a 'can-do' attitude, be committed to RCSI ORI and its development; demonstrate enthusiasm and passion for the role. We are all too aware that imposter syndrome and the confidence gap can sometimes stop fantastic candidates putting themselves forward, so please do submit an application - we'd love to hear from you. Application Process Please apply online no later than 5pm on the closing date of November 26th 2025 with your CV and Cover Letter. Informal Enquiries can be directed to Roger Preston (). Click here to read our Recruitment and Selection Policy for Researcher. Garda vetting and occupational health review may be required for this role, depending on the nature of the duties and responsibilities. Further information will be provided during the recruitment process. Eligibility to Work in Ireland Visa sponsorship is available for candidates who fully meet the essential criteria of the role. Candidates who require a work permit or hosting agreement are welcome to apply. Proof of eligibility documentation will be required at a later stage in the recruitment process. Please note that sponsorship is subject to approval by the relevant Irish authorities and role-specific eligibility.