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Postdoc opportunities: cancer genomics for regulatory rna therapeutics

Dublin
SFBI
Posted: 7 February
Offer description

Postdoc Opportunities: Cancer Genomics for Regulatory RNA TherapeuticsDescriptionPostdoc Opportunities: Cancer Genomics for Regulatory RNA TherapeuticsAre you an ambitious researcher looking for a challenge at the forefront of cancer, genome editing and RNA therapeutics?The Laboratory for Genomics of Long Noncoding RNAs and Disease (GOLD Lab) is hiring! Based in the Conway Institute at University College Dublin (Ireland), we are an interdisciplinary team of passionate researchers dedicated to understanding the roles of long non-protein-coding RNAs (lncRNAs) in disease. We love to create new tools based on CRISPR-Cas genome editing and bioinformatics to discover new and interesting lncRNAs. We participate actively in major international consortia (Genomics England, GENCODE, FANTOM).We strive to foster a supportive, collaborative, successful and fun lab community.The Project: We have openings for two Postdoctoral Researchers funded by a prestigious Research Ireland (SFI) Frontiers for the Future Award. This project will investigate how tumour mutations act through lncRNAs to drive cancer, and how we can harness this for novel therapies. Our unique dataset is 16,000 whole tumour genomes from Genomics England. We will apply cutting edge methods including advanced genome editing (Prime editing, CRISPRi), oligonucleotide therapeutics and machine learning. The project will benefit from world-leading Collaborators Catriona Dowling (RCSI, disease modelling) and Colm Ryan (UCD, computer science).We are recruiting two distinct profiles:

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