A top-level research position is available to lead analytical and mechanistic development workstream for a dual-cell therapy targeting neonatal hypoxia-associated brain injury.
Key Responsibilities:
* Develop in vitro models for neonatal brain injury, validate their reproducibility and translational relevance, and plan and execute proteomic and RNA-seq studies to elucidate the mechanism of action of MSC/ECFC co-therapy.
* Integrate multi-omics datasets to define therapeutic pathways and biomarkers.
Required Expertise:
* Hands-on experience with mesenchymal stromal cells (MSCs) and endothelial colony-forming cells (ECFCs).
* Demonstrated expertise with proteomics and transcriptomics (RNA-seq) for mechanism-of-action studies.
* Ability to define and assess Critical Quality Attributes (CQAs) for cell therapy products.
Successful Candidate:
The ideal candidate will have a strong scientific background in cellular therapies and expertise in model development, data analysis, and interpretation.
This role offers an exciting opportunity to contribute to cutting-edge research in cell therapies and make a meaningful impact in the field of neonatal brain injury.