Job Opportunity:
SK biotek Ireland is seeking a highly skilled Senior Organic Chemist to join its R&D team on a temporary basis. The successful candidate will have experience in synthetic organic chemistry and be responsible for providing support for all aspects of new and existing chemical processes development, technology transfer, process scale-up, process safety, process monitoring, and process troubleshooting.
About the Role:
The Senior Organic Chemist will lead development projects in the laboratory, provide technical support to the manufacture of APIs and intermediates, identify and implement projects to optimize processes, and collaborate with R&D analytical chemists and Operations engineers on new products introduction and scale up activities.
Key Responsibilities:
* Lead development projects in the laboratory, including route scouting and route development, proof of concept, crystallisation optimization, and process safety assessment.
* Provide technical support to the manufacture of APIs and intermediates manufactured at SK biotek Ireland, with a focus on optimization and investigation support.
* Identify and implement projects to optimize processes, considering scale-up and manufacturing aspects and Critical to Quality Attributes.
* Leverage data monitoring and PAT tools in the laboratory such as FBRM, Raman, IR, as required. Identify and implement new technologies to support development for business needs.
* Collaborate with R&D analytical chemists and Operations engineers on new products introduction and scale up activities, including process development in the laboratory, customer engagement, troubleshooting, documentation, and campaign readiness.
* Support chemistry assessments for new products as required.
* Lead optimization projects on throughput and yield in collaboration with Operations engineers.
* Support continuous process verification through collection and trending of data for commercial products, identifying Out of Trends (OOT) and Statistical Alert Events (SAE) and leading investigations where required with support from engineers and analytical chemists.
* Actively participate in manufacturing campaign performance support teams.
* Lead and support quality and safety investigations.
Requirements:
* Strong technical background in chemistry.
* PhD in organic chemistry.
* Strong interpersonal and communicational skills and demonstrated ability to work across a matrix.
* Excellent problem-solving skills and commitment to continuous improvement.
* Experience in project management, troubleshooting and continuous process verification.
* Demonstrated capability in the use of standard tools for root cause analysis and standard statistical tools.
* Demonstrated capability in the use of various analytical/diagnostic tools including PAT, chromatography and process safety.
* Ensure that GMP, Quality, Health & Safety are considered in all aspects of the role.
About Us:
A career with purpose and a chance to work with a world-leader in contract development and manufacturing in a fast-paced, dynamic, and growing organisation. We believe we enhance patients' lives and need you to help us achieve this mission to 'make what matters for a healthy, happier world'. At SK biotek Ireland, we remind each one of us that what we do matters, and our mission is to act as a catalyst in a chain of events that helps millions of people all over the globe.