We have a new opportunity for Senior Research Fellow with our client based in Dublin.
Location: Dublin, Ireland Contract: 30-Month Fixed Term Salary & Benefits: Competitive package including pension, private health insurance, income protection, 25 days annual leave (plus additional company days), flexible working, and strong career development support.
Role Overview We are seeking a Senior Research Fellow to join a multidisciplinary consortium focused on advancing a dual-cell therapy for neonatal hypoxia-associated brain injury.
This is a high-impact translational research role, supporting the transition from preclinical development toward First-In-Human, Phase 1 clinical trials.
The role offers the opportunity to lead analytical development, explore critical quality attributes (CQAs), and develop potency matrices while driving innovative research in neurovascular injury models.
Key Responsibilities: Design, optimize, and validate in vitro hypoxia and neurovascular models relevant to neonatal brain injury.
Conduct proteomic and transcriptomic analyses (RNA-seq) to study mechanisms of action for MSC and ECFC co-therapy.
Integrate multi-omics data to identify therapeutic pathways and biomarkers.
Define and monitor CQAs (identity, purity, viability, immunophenotype) and develop potency assays.
Develop release assays ensuring product consistency and regulatory compliance.
Lead a multidisciplinary team, managing project milestones, deliverables, and data quality.
Mentor junior researchers and Ph D students.
Prepare manuscripts, grant reports, and contribute to regulatory submissions.
Present findings at scientific conferences, consortium meetings, and stakeholder briefings.
Essential Criteria Ph D in Neuroscience, Cell Therapy, Regenerative Medicine, Biotechnology, or a related field.
4+ years post-Ph D experience in relevant research areas.
Proven leadership with a strong publication record, international conference presentations, and supervision of junior staff/Ph D students.
Expertise in cell biology (MSCs, ECFCs) and neuronal/neurovascular models.
Hands-on experience with omics technologies (proteomics, transcriptomics) and data analysis.
Experience in defining CQAs, potency assays, and ATMP release criteria.
Familiarity with regulatory frameworks for ATMPs and translational research toward clinical trials.
Strong project management, analytical, and communication skills.
For further details on this opportunity, please reach out to Gillian Nicholson to Skills: Neurovascular researcher Neurovascular Postdoctoral Researcher