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Upstream senior scientist 1

Cork
Biomarin International Limited
Scientist
Posted: 11 May
Offer description

About BioMarin

BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health.

We have been applying our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities.

Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need.

We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science.

About Technical Operations

BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market.

These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients.



Senior Scientist 1, Biologics Centre of Excellence (BCo E)


Onsite, Shanbally

The Technical Development and Services BCo E lab is seeking an Upstream Senior Scientist 1 to lead and grow a 3+ member team.

This individual will be a technical leader in Drug Substance Technologies and coordinate goals, support resourcing, and lead technical projects supporting commercial manufacturing.

The team will oversee the activities and professional development of junior scientists and research associates as they develop, characterise, and transfer upstream biomanufacturing processes for our biologics pipeline programs.

* Design and execution of experiments in the laboratory
* Utilising and refining bench-top bioreactor and fermentor process models
* Purification or analytics of intermediate samples to assess performance

Responsibilities:

* Leading team of scientists and research associates for upstream activities
* Directs projects of a complex nature; oversees experimental, tech transfer, and manufacturing support activities and investigations
* Participate in efforts to define, manage, and/or complete innovation projects that advance technical capabilities
* Track team progress against project timelines, generate regular status updates and communicate progress, resourcing needs and issues to leadership

Requirements:

* Ph D in Biology or a related field, or equivalent relevant experience, and more than five years of experience in the biotechnology industry; MS with 10+ years; BS with 12+ years.
* Experience with cell culture processing platforms, including bioreactor/fermentor optimization and scale-up.
* Process characterization and risk assessment experience necessary
* Ability to perform statistical design of experiments (DoE), data analysis and interpret and present results
* Clear technical writing and editing to author or oversee generation of technical reports


Equal Opportunity Employer
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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